gene 775 words KG: WDR45B
Contents

WDR45B — WD Repeat Domain 45B

🧬 Gene Info
Gene SymbolWDR45B
Full NameWD Repeat Domain 45B
AliasesWDR45B Protein
Functionis a WD repeat protein that plays a critical role in autophagy, specifically in the formation and function of autophagosomes.
Primary Expressionthe brain [@toney2019]
Molecular Weight44.6 kDa
PathwaysPI3K
Ensembl IDENSG00000160087
GeneCardsWDR45B
Human Protein AtlasWDR45B
WD repeats5-6 WD repeat motifs forming a beta-propeller
N-terminal regionInvolved in protein interactions
Autophagosome formationRequired for initiation of autophagy
Selective autophagyInvolved in specific cargo recognition
Lipid metabolismAffects membrane dynamics
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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