| Gene Symbol | VPS18 |
| Full Name | Vacuolar Protein Sorting 18 homolog |
| Chromosome | 15q14 |
| Protein Type | Vesicle trafficking, HOPS complex subunit |
| Function | encodes a critical protein component of the HOPS (Homotypic fusion and Vacuole Protein Sorting) complex, which is essential for endosomal trafficking and lysosomal biogenesis[@huizing2005]. |
| Amino Acids | 796 aa |
| UniProt ID | Q9P258 |
| NCBI Gene ID | 8875 |
| Ensembl ID | ENSG00000134882 |
| GeneCards | VPS18 |
| Human Protein Atlas | VPS18 |
| RING finger domain | N-terminal RING finger involved in protein interactions |
| α-solenoid domain | Middle region mediates complex assembly |
| C-terminal domain | Interacts with other HOPS subunits |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Databases | GeneCardsHPASTRING |
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