| Gene Symbol | USH1G |
| Full Name | USHER Syndrome 1G Protein (SANS) |
| Chromosome | 17q25.1 |
| Protein Type | Gene |
| Function | is a critical gene involved in the development and maintenance of the auditory and visual systems. |
| Primary Expression | both inner and outer hair cells of the cochlea - Stereocilia: Localizes to the stereociliary tips and shafts - Vestibular system: Present in h |
| Molecular Weight | 51 kDa |
| Amino Acids | 460 aa |
| GeneCards | USH1G |
| Human Protein Atlas | USH1G |
| Ankyrin (ANK) repeat domain | Three ankyrin repeats (residues 50-180) that mediate protein-protein interactions |
| SAM (Sterile Alpha Motif) domain | Located in the central region (residues 200-260) |
| PDZ-binding motif | The extreme C-terminus contains a canonical PDZ-binding sequence (S/T-X-L/V) |
| Hair cells | Expressed in both inner and outer hair cells of the cochlea |
| Stereocilia | Localizes to the stereociliary tips and shafts |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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