gene 2,426 words KG: UCP4
Contents

UCP4 Gene

🧬 Gene Info
Gene SymbolUCP4
AliasesUncoupling Protein 4
Chromosome6p25.3
Protein TypeGene
Functionis a mitochondrial carrier protein primarily expressed in the nervous system.
Primary Expressionthe nervous system
Molecular Weight34 kDa
Amino Acids307 aa
Exons9
NCBI Gene ID285102
GeneCardsUCP4
Human Protein AtlasUCP4
Transport mechanismAlternating access - substrate binding triggers conformational changes
Substrate specificityPredominantly transports protons, may also transport other small molecules
N-terminal targeting sequenceMitochondrial targeting peptide (first ~20 amino acids)
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtHPASTRING

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