| Gene Symbol | TYDP1 |
| Full Name | Tyrosyl-DNA Phosphodiesterase 1 |
| Chromosome | 14q32.12 |
| Protein Type | Enzyme |
| Function | is a gene located on chromosome 14q32. |
| Molecular Weight | 68.5 kDa |
| Amino Acids | 608 aa |
| Exons | 14 |
| GeneCards | TYDP1 |
| Human Protein Atlas | TYDP1 |
| N-terminal PINc domain (residues 1-500) | The catalytic nuclease domain with a beta-helix barrel structure containing four conserved acidic residues (D275, E277, H394, H423) that coordinate two metal ions (Mg2+ or Mn2+) for catalysis. |
| C-terminal region (residues 500-608) | Regulatory region with proposed nuclear localization signal and protein-protein interaction motifs. |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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