| Gene Symbol | TXNDC5 |
| Full Name | Thioredoxin Domain Containing 5 |
| Chromosome | 6p24.3 |
| Function | TXNDC5 exhibits the following key functions |
| Primary Expression | Brain, Heart, Lung, Liver, Kidney, Platelets |
| UniProt ID | Q8N7T0 |
| NCBI Gene ID | 81567 |
| Ensembl ID | ENSG00000213186 |
| OMIM | 614008 |
| GeneCards | TXNDC5 |
| Human Protein Atlas | TXNDC5 |
| Protein Disulfide Isomerase Activity | Catalyzes disulfide bond formation and rearrangement in nascent proteins[@kojer2015] |
| ER Redox Homeostasis | Maintains the ER in a reduced state necessary for proper protein folding |
| Anti-apoptotic Function | Protects against ER stress-induced apoptosis through inhibition of CHOP expression[@tanaka2014] |
| Angiogenesis Regulation | Modulates endothelial cell function and blood vessel formation[@zhang2018] |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!