| Gene Symbol | Tripartite Motif Containing 55 |
| Chromosome | 8q24.13 |
| Protein Type | Ligase |
| Function | is a muscle-specific E3 ubiquitin ligase that plays critical roles in muscle protein degradation, sarcomere maintenance, and cellular protein quality control[@centner2001]. |
| Primary Expression | skeletal and cardiac muscle, where it functions as an E3 ubiquitin ligase involved in: |
| Gene Type | Protein Coding |
| UniProt ID | Q9C0B1 |
| NCBI Gene ID | 80316 |
| Ensembl ID | ENSG00000138182 |
| OMIM | 608598 |
| Sarcomere maintenance | Targets structural proteins for ubiquitination and degradation |
| Muscle protein turnover | Regulates degradation of contractile proteins |
| Troponin degradation | Interacts with troponin complex components |
| Myosin binding | Associates with myosin binding proteins |
| High expression | Skeletal muscle, cardiac muscle |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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