gene 1,866 words KG: TOMM40L
Contents

TOMM40L — Translocase of Outer Mitochondrial Membrane 40 Like

🧬 Gene Info
Gene SymbolTOMM40L
Full NameTranslocase of Outer Mitochondrial Membrane 40 Like
Chromosome1q21.3
FunctionThis process is critical for mitochondrial biogenesis and function:
Molecular Weight43 kDa
Amino Acids384 aa
Exons9
Ensembl IDENSG00000146215
GeneCardsTOMM40L
Human Protein AtlasTOMM40L
TOMM20Receptor protein that recognizes mitochondrial targeting signals
TOMM22Central receptor component
TOMM40Channel-forming subunit (TOMM40L is a paralog)
TOMM5Small accessory subunit
TOMM7Accessory subunit for complex stability
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (25)

Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Lysosomal Membrane Repair Enhancement
Score: 0.54
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
← Prevpg 2/2

Related Analyses (14)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
nct05508789
clinical_trial · Pages share 4 hypotheses
MK-1167 Phase 2 AD Trial (MK-1167-008)
clinical · Pages share 4 hypotheses
A Placebo-Controlled, Double-Blind, Parallel-Group, 18-
clinical · Pages share 4 hypotheses
LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy
clinical · Pages share 4 hypotheses

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