gene 1,422 words KG: TLR10
Contents

TLR10 Gene

🧬 Gene Info
Gene SymbolTLR10
Full NameToll-Like Receptor 10
Chromosome4p14
Protein TypeReceptor
Functionis a type I transmembrane pattern recognition receptor belonging to the TLR1/2/6/10 subfamily.
Ensembl IDENSG00000150045
GeneCardsTLR10
Human Protein AtlasTLR10
Co-receptor functionActs primarily as a co-receptor rather than a primary pattern recognition receptor
Modulatory effectsCan inhibit signaling from TLR2-containing heterodimers
Adaptive immunityInvolved in B cell responses and antibody production
Brain expressionPresent in microglia and other brain cells
LRR 3Contains an insertion unique among TLRs
TIR domainHas specific residues that affect signaling
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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