| Gene Symbol | TGFBR2 |
| Full Name | Transforming Growth Factor Beta Receptor 2 |
| Chromosome | 3p24.1 |
| Protein Type | Receptor |
| Function | is an essential component of TGF-beta signaling in the nervous system. |
| Primary Expression | cerebral blood vessels, critical for BBB function[@nitta2019] |
| UniProt ID | P37173 |
| NCBI Gene ID | 7048 |
| Ensembl ID | ENSG00000163513 |
| OMIM | 190182 |
| GeneCards | TGFBR2 |
| Human Protein Atlas | TGFBR2 |
| Extracellular domain | Contains TGF-beta binding regions that recognize ligand-bound type III receptors |
| Transmembrane domain | Single-pass transmembrane helix |
| TGF-beta signal initiation | Primary receptor for TGF-beta1, TGF-beta2, and TGF-beta3[@gordon2020] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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