| Gene Symbol | TCF4-GENE |
| Aliases | TCF4_GENE |
| Chromosome | 18q21.2 |
| Protein Type | Transcription Factor |
| Function | is a basic helix-loop-helix (bHLH) transcription factor encoded by the TCF4 gene on chromosome 18q21. |
| Primary Expression | the developing brain, with persistent expression in adulthood particularly in: - Hippocampal CA1-CA3 regions - Cerebral cortex (layer 2/3 pyramidal ne |
| Amino Acids | 010 aa |
| Exons | 20 |
| GeneCards | TCF4-GENE |
| Human Protein Atlas | TCF4-GENE |
| bHLH DNA-binding domain | Recognizes E-box consensus sequences (CANNTG) |
| C-terminal dimerization domain | Mediates heterodimer formation with other bHLH proteins |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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