| Gene Symbol | TBX2 |
| Full Name | T-Box Transcription Factor 2 |
| Chromosome | 17q23.2 |
| Protein Type | Transcription Factor |
| Function | is a member of the T-box family of transcription factors that play critical roles in embryonic development, tissue patterning, and cellular differentiation. |
| Primary Expression | the developing and adult brain, where it regulates genes involved in neuronal differentiation, survival, and function |
| Subcellular Localization | **Sumoylation**: Sumoylation of TBX2 may modulate its repressive functions |
| Molecular Weight | 75 kDa |
| Amino Acids | 680 aa |
| Exons | 8 |
| UniProt ID | Q9URJ3 |
| NCBI Gene ID | 6903 |
| GeneCards | TBX2 |
| Human Protein Atlas | TBX2 |
| Activation Domain | Located at amino acids 350-450, this region interacts with transcriptional co-activators and histone acetyltransferases |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
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