| Gene Symbol | TBL2 |
| Chromosome | 7q11.23 |
| Function | encodes a WD40 repeat-containing protein that plays important roles in cellular signal transduction, protein quality control, and transcriptional regulation. |
| Primary Expression | Purkinje cells and granule cells |
| Amino Acids | 60 aa |
| GeneCards | TBL2 |
| Human Protein Atlas | TBL2 |
| N-terminal domain | Involved in protein targeting and localization |
| WD40 repeat region | Forms the structural core for protein-protein interactions |
| C-terminal region | Contains regulatory elements and post-translational modification sites |
| Substantia nigra | Present in dopaminergic neurons of the pars compacta |
| Cerebellum | Expressed in Purkinje cells and granule cells |
| Hypothalamus | Moderate expression in various nuclei |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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