| Gene Symbol | TARS1 |
| Full Name | Threonyl-tRNA Synthetase 1 |
| Aliases | ThrRS |
| Function | TARS1 (Threonyl-tRNA Synthetase 1) is a human gene encoding threonyl-tRNA synthetase (ThrRS), an essential aminoacyl-tRNA synthetase that catalyzes the attachment of threonine to its cognate tRNA. |
| Amino Acids | 724 aa |
| GeneCards | TARS1 |
| Human Protein Atlas | TARS1 |
| N-terminal domain | Contains the editing site that clears mischarged amino acids |
| Core catalytic domain | Class II synthetase fold with the characteristic KMSKS loop |
| C-terminal domain | Involved in dimerization and extra-translational functions |
| Appendage domains | Include sequences for nuclear localization and protein-protein interactions |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!