| Gene Symbol | SURF6 |
| Full Name | Ribosome Biogenesis Factor |
| Aliases | SURF6 Homolog |
| Function | Its primary functions include |
| Ensembl ID | ENSG00000148229 |
| GeneCards | SURF6 |
| Human Protein Atlas | SURF6 |
| SURF4 | Co-assembles in the ER-Golgi pathway |
| NOP53 | Ribosome assembly cofactor |
| WDR74 | WD repeat-containing protein 74 |
| Translation deficit | Reduced protein synthesis in AD brain correlates with cognitive decline |
| Nucleolar stress | SURF6 downregulation triggers p53-dependent apoptosis 2 |
| Tau pathology | Ribosome dysfunction contributes to tau-induced neurodegeneration |
| ER stress | Impaired ribosome biogenesis increases ER stress |
| Protein homeostasis | Defects in translation machinery disrupt proteostasis |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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