gene 2,774 words KG: STX2
Contents

STX2 — Syntaxin 2

🧬 Gene Info
Gene SymbolSTX2
Full NameSyntaxin 2
Chromosome12q24.31
Functionis a member of the syntaxin family of SNARE (Soluble NSF Attachment Protein Receptor) proteins that mediate membrane fusion events in eukaryotic cells.
Primary Expressionboth excitatory and inhibitory neurons - Synaptic localization: Primarily presynaptic, with some postsynaptic presence - Non-neuronal tissues:
Amino Acids288 aa
UniProt IDP32856
NCBI Gene ID2054
Ensembl IDENSG00000120280
OMIM132050
GeneCardsSTX2
Human Protein AtlasSTX2
N-terminal domain (1-60)Regulatory domain that interacts with munc18 proteins
SNARE domain (60-230)The central coiled-coil domain that forms the SNARE complex
Linker region (230-265)Flexible hinge region
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsHPASTRING

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