| Gene Symbol | STK24 |
| Chromosome | 13q12.11 |
| Protein Type | Serine/Threonine Kinase |
| Function | is a member of the Ste20 family of serine/threonine kinases. |
| Primary Expression | the brain and has been increasingly recognized for its involvement in neurodegenerative diseases, particularly Alzheimer's disease (AD) and Parkinson' |
| Amino Acids | 462 aa |
| Exons | 12 |
| Pathways | MAPK Signaling, MAPK, MAPK pathway, PI3K, NF-κB |
| GeneCards | STK24 |
| Human Protein Atlas | STK24 |
| N-terminal Kinase Domain | Catalytic domain responsible for ATP binding and phosphoryl transfer (residues 1-280) |
| Coiled-coil Region | Mediates protein-protein interactions and dimerization (residues 281-350) |
| C-terminal Regulatory Domain | Contains autophosphorylation sites that regulate kinase activity (residues 351-462) |
| Synaptic Plasticity | Regulates dendritic spine morphology and synaptic strength through modulation of actin cytoskeleton dynamics [6] |
| Axon Guidance | Controls growth cone collapse and axon pathfinding through semaphorin signaling |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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