| Gene Symbol | SLC6A9 |
| Aliases | Glycine Transporter 2 |
| Chromosome | 1p34.1 |
| Function | The SLC6A9 locus is on chromosome 1p34.1 and encodes a 12-transmembrane-domain protein of approximately 638 amino acids. |
| Primary Expression | presynaptic terminals of glycinergic neurons in the brainstem and spinal cord |
| Amino Acids | 638 aa |
| GeneCards | SLC6A9 |
| Human Protein Atlas | SLC6A9 |
| N-terminal intracellular domain | Contains regulatory serine residues and motifs for interaction with scaffolding proteins |
| Transmembrane core | Forms the substrate-binding pocket (S1 site) with high affinity for glycine |
| Extracellular loops | Heavily glycosylated at conserved NXT motifs |
| C-terminal intracellular tail | Contains a PDZ-binding motif (Ser-Ser-Leu) for interaction with gephyrin and other synaptic scaffold proteins |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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