| Gene Symbol | SLC6A8 |
| Aliases | Creatine Transporter |
| Chromosome | Xq28 |
| Function | encodes an 11-transmembrane-domain protein of approximately 635 amino acids. |
| Primary Expression | most tissues, with particularly high expression in kidney, brain, muscle, and heart |
| Amino Acids | 635 aa |
| GeneCards | SLC6A8 |
| Human Protein Atlas | SLC6A8 |
| N-terminal intracellular domain | Contains regulatory serine residues subject to phosphorylation |
| Transmembrane core | Forms the substrate-binding site (S1) and the gate mechanism |
| Large extracellular loop 1 | Contains glycosylation sites important for surface expression |
| C-terminal intracellular tail | Contains PDZ-binding motif for scaffolding protein interaction |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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