gene 1,345 words KG: SLC3A1
Contents

SLC3A1 — Solute Carrier Family 3 Member 1

🧬 Gene Info
Gene SymbolSLC3A1
Full NameSolute Carrier Family 3 Member 1
Chromosome2p16.3
FunctionEssential amino acid transport:
Primary Expressionthe kidney and intestinal epithelium where it mediates reabsorption of cystine and dibasic amino acids [@palacin2005]
Subcellular Localization- **Proximal renal tubule**: Apical membrane of S1-S2 segments
Molecular Weight79 kDa
Amino Acids683 aa
Exons8
UniProt IDQ07817
NCBI Gene ID10251
Ensembl IDENSG00000166391
GeneCardsSLC3A1
Human Protein AtlasSLC3A1
Single transmembrane helix (aa 481-503)Anchors the protein in the plasma membrane
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38

Related Analyses (4)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.