gene 2,547 words KG: SLC39A12
Contents

SLC39A12 — Solute Carrier Family 39 Member 12 (ZIP12)

🧬 Gene Info
Gene SymbolSLC39A12
Full NameSolute Carrier Family 39 Member 12 (ZIP12)
Chromosome9q34.2
Protein FamilySLC39A (ZIP) transporter family
Protein TypeTransporter
Functionis a member of the solute carrier family 39 (ZIP) metal transporters.
Primary ExpressionHigh in brain (cortex, hippocampus); moderate in testis
Subcellular LocalizationPlasma membrane
Amino Acids628 aa
GeneCardsSLC39A12
Human Protein AtlasSLC39A12
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (8)

SASP-Mediated Complement Cascade Amplification
Score: 0.91
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88
Autophagosome Maturation Checkpoint Control
Score: 0.71
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69
VCP-Mediated Autophagy Enhancement
Score: 0.57
APOE-Dependent Autophagy Restoration
Score: 0.85
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Oligodendrocyte White Matter Vulnerability
Score: 0.65

Related Analyses (5)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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