| Gene Symbol | SGSH |
| Full Name | N-Sulfoglucosamine Sulfohydrolase |
| Chromosome | 17q25.3 |
| Protein Type | Enzyme |
| Function | SGSH encodes sulfamidase (N-sulfoglucosamine sulfohydrolase), a lysosomal enzyme that catalyzes the removal of N-linked sulfate groups from heparan sulfate |
| UniProt ID | P51688 |
| NCBI Gene ID | 6448 |
| Ensembl ID | ENSG00000138323 |
| OMIM | 605270 |
| GeneCards | SGSH |
| Human Protein Atlas | SGSH |
| Substrate | N-sulfoglucosamine residues in heparan sulfate chains |
| Product | N-acetylglucosamine (or glucosamine) + sulfate |
| Optimal pH | ~5.0 (lysosomal) |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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