gene 3,161 words KG: RNASEK
Contents

RNASEK — Ribonuclease Kappa

🧬 Gene Info
Gene SymbolRNASEK
Full NameRibonuclease Kappa
Chromosome17p11.2
Functionis a gene encoding a cytoplasmic endoribonuclease that degrades circular RNAs (circRNAs).
Subcellular Localization**Primary location**: Cytoplasm
Molecular Weight31.2 kDa
Amino Acids278 aa
Exons8
PathwaysNF-κB
UniProt IDQ9BYX4
NCBI Gene ID124540
Ensembl IDENSG00000166987
OMIM619356
GeneCardsRNASEK
Human Protein AtlasRNASEK
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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Related Hypotheses (20)

APOE-Dependent Autophagy Restoration
Score: 0.85
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81

Related Analyses (5)

Astrocyte Reactivity Subtypes in Neurodegeneration
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived

Related Experiments (5)

Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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