| Gene Symbol | RCN1 |
| Function | encodes a calcium-binding protein that localizes to the endoplasmic reticulum (ER) and is a member of the CREC (calumenin-RCN-ERC) family of EF-hand proteins. |
| Primary Expression | various cancers: |
| Amino Acids | 332 aa |
| Ensembl ID | ENSG00000100994 |
| GeneCards | RCN1 |
| Human Protein Atlas | RCN1 |
| Calumenin (CALU) | Widely expressed EF-hand protein |
| RCN1 (Reticulocalbin 1) | Brain-enriched member |
| RCN2 (Reticulocalbin 2) | ESCUBE-related protein |
| ERC1/2 (ERC-55) | Calcium-binding proteins |
| Signal peptide | N-terminal targeting sequence (1-20 aa) |
| EF-hand domains | Six calcium-binding motifs (70-300 aa) |
| ER retention sequence | C-terminal KDEL motif |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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