| Gene Symbol | RASGRF2 |
| Full Name | Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 |
| Chromosome | 5q14.1 |
| Function | is a calcium/calmodulin-regulated guanine nucleotide exchange factor (GEF) that activates Ras and Rac GTPases. |
| Primary Expression | the striatum, hippocampus, and cortex, making it particularly relevant to neurodegenerative diseases including Parkinson's disease (PD) and Alzheimer' |
| Subcellular Localization | CaMKII regulates RasGRF2 through direct phosphorylation |
| Amino Acids | 1355 aa |
| UniProt ID | O14827 |
| NCBI Gene ID | 10237 |
| Ensembl ID | ENSG00000101938 |
| OMIM | 608099 |
| GeneCards | RASGRF2 |
| Human Protein Atlas | RASGRF2 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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