| Gene Symbol | RAPGEF1 |
| Full Name | Rap Guanine Nucleotide Exchange Factor 1 (C3G) |
| Chromosome | 9q34.13 |
| Function | is a critical signaling molecule that serves as a guanine nucleotide exchange factor (GEF) for small GTPases Rap1 and R-Ras. |
| Primary Expression | the central nervous system, particularly in hippocampal neurons, cortical pyramidal cells, and cerebellar Purkinje cells |
| Molecular Weight | 116 kDa |
| Amino Acids | 047 aa |
| Exons | 23 |
| UniProt ID | Q9Y238 |
| NCBI Gene ID | 2889 |
| Ensembl ID | ENSG00000107281 |
| OMIM | 600996 |
| GeneCards | RAPGEF1 |
| Human Protein Atlas | RAPGEF1 |
| Rap1 binding interface | Specific interaction with Rap1 GTPase |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!