| Gene Symbol | RACGAP1 |
| Full Name | Rac GTPase Activating Protein 1 |
| Chromosome | 12q13.12 |
| Protein Type | GTPase activating protein (GAP) |
| Function | is a critical GTPase activating protein that regulates the Rho family GTPases Rac1, Cdc42, and RhoA. |
| Molecular Weight | 71 kDa |
| UniProt ID | P47738 |
| NCBI Gene ID | 10505 |
| Ensembl ID | ENSG00000113889 |
| GeneCards | RACGAP1 |
| Human Protein Atlas | RACGAP1 |
| GAP domain | Catalyzes GTP hydrolysis on Rho family GTPases (Rac1, Cdc42, RhoA), converting active GTP-bound form to inactive GDP-bound form |
| CRIB domain | Cdc42/Rac interactive binding domain for interaction with Cdc42 and Rac1 |
| Phosphorylation sites | Multiple serine/threonine phosphorylation sites regulate its activity and localization |
| Mitosis and cell division | Critical for central spindle assembly, cytokinesis, and accurate chromosome segregation. RACGAP1 localizes to the central spindle and midbody during anaphase and telophase. [@matsumura2005] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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