| Gene Symbol | RAB25 |
| Chromosome | 1q22. |
| Protein Type | Gene |
| Function | is a gene/protein involved in various cellular processes relevant to neurodegenerative diseases. |
| Primary Expression | various tissues with highest expression in: - Kidney (high expression in tubular epithelial cells) - Liver (hepatocytes) - Brain (moderate expression |
| Molecular Weight | 24 kDa |
| Amino Acids | 219 aa |
| Exons | 7 |
| GeneCards | RAB25 |
| Human Protein Atlas | RAB25 |
| Prenylation | C-terminal geranylgeranylation is essential for membrane association |
| Phosphorylation | Multiple serine/threonine phosphorylation sites identified |
| Ubiquitination | Regulates protein stability and localization |
| Polarized trafficking | Regulates transport in epithelial cells, particularly apical membrane delivery and polarized sorting |
| Lysosomal function | Controls trafficking to lysosomes and late endosomes, influencing lysosomal positioning and function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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