| Gene Symbol | PTPS |
| Full Name | 6-Pyruvoyl-Tetrahydropterin Synthase |
| Chromosome | 11q22.2 |
| Function | BH4 biosynthesis, neurotransmitter synthesis |
| Primary Expression | both neurons and glia, with particularly high expression in dopaminergic neurons of the substantia nigra pars compacta[@lanz2008] |
| Amino Acids | 145 aa |
| Exons | 6 |
| UniProt ID | Q16473 |
| Ensembl ID | ENSG00000132932 |
| GeneCards | PTPS |
| Human Protein Atlas | PTPS |
| Brain | Substantia nigra, striatum, hippocampus, cortex |
| Liver | Primary site of BH4 biosynthesis |
| Adrenal glands | High catecholamine synthesis |
| Kidney | Tetrahydrobiopterin metabolism |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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