gene 1,535 words KG: PSPN
Contents

PSPN — Persephin

🧬 Gene Info
Gene SymbolPSPN
Full NamePersephin
Chromosome19p13.3
Protein FamilyGDNF family
Functionencodes a neurotrophic factor belonging to the GDNF (glial cell line-derived neurotrophic factor) family of proteins.
Primary Expressionmost neurons that respond to GDNF family ligands
Molecular Weight25 kDa
UniProt ID[O60543](https://www.uniprot.org/uniprot/O60543)
Ensembl IDENSG00000163389
OMIM602565
GeneCardsPSPN
Human Protein AtlasPSPN
Multiple exonsSpanning approximately 2.5 kb of genomic DNA
Signal peptideSequence for secretory pathway targeting
Cysteine-rich domainConserved motif characteristic of the GDNF family
Associated DiseasesParkinson's disease, ALS
DatabasesGeneCardsNCBI GeneHPASTRING

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