| Gene Symbol | PSMA2 |
| Full Name | Proteasome Subunit Alpha 2 |
| Chromosome | 7p14.3 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| UniProt ID | PSMA2 |
| NCBI Gene ID | 5683 |
| Ensembl ID | ENSG00000146576 |
| OMIM | 176842 |
| GeneCards | PSMA2 |
| Human Protein Atlas | PSMA2 |
| N-terminal domain | Forms the substrate entry portal; contains the HbYX motif critical for 19S regulatory particle binding |
| Core domain | Seven α-helices arranged in a barrel-like structure |
| Binding interface | Forms contacts with adjacent α subunits (PSMA1, PSMA5, PSMA7) in the alpha ring |
| Synaptic protein turnover | Rapid degradation of synaptic proteins for plasticity |
| Neuroprotection | Clearance of toxic protein aggregates |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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