| Gene Symbol | PPP1R9B |
| Full Name | Spinophilin |
| Chromosome | 17q21.33 |
| Function | regulatory subunit critical for synaptic plasticity |
| UniProt ID | [Q9Y2J8](https://www.uniprot.org/uniprot/Q9Y2J8) |
| Ensembl ID | ENSG00000127314 |
| GeneCards | PPP1R9B |
| Human Protein Atlas | PPP1R9B |
| Directs PPP1 to dendritic spines | the RVxF motif in spinophilin binds the PPP1 catalytic subunit |
| Recruits PPP1 to postsynaptic densities | targets both NMDA and AMPA receptor complexes |
| Substrate specificity | modulates PPP1 activity toward specific substrates including: |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!