| Gene Symbol | PEX6 |
| Aliases | Peroxisome Biogenesis Factor 6, Page for PEX6 Protein |
| Chromosome | 6p21.1 |
| Protein Type | Gene |
| Function | PEX6, in complex with PEX1 (another AAA ATPase), extracts PEX5 from the peroxisomal membrane. |
| Molecular Weight | 104 kDa |
| Amino Acids | 979 aa |
| Exons | 13 |
| GeneCards | PEX6 |
| Human Protein Atlas | PEX6 |
| ATP Binding | PEX6 binds ATP in its AAA domains |
| Conformational Changes | ATP hydrolysis drives conformational changes in the hexamer |
| PEX5 Extraction | These conformational changes pull ubiquitinated PEX5 from the membrane |
| ATP Hydrolysis | Hydrolysis of ATP releases PEX6 for another cycle |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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