| Gene Symbol | PEX12 |
| Chromosome | 17q12 |
| Protein Family | RING finger protein family |
| Function | is a RING finger peroxisomal membrane protein that functions as an E3 ubiquitin ligase essential for peroxisome biogenesis. |
| Subcellular Localization | Peroxisomal membrane |
| Molecular Weight | 40 kDa |
| Amino Acids | 359 aa |
| UniProt ID | O00312 |
| GeneCards | PEX12 |
| Human Protein Atlas | PEX12 |
| N-terminal region | Cytoplasmic domain for PEX5 interaction |
| RING finger domain | C3HC4-type zinc finger for E3 ligase activity |
| C-terminal region | Peroxisomal membrane anchor |
| PEX5-binding site | Direct interaction with peroxin |
| E3 ubiquitin ligase activity | Catalyzes ubiquitination of PEX5 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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