gene 1,220 words KG: PDE6B
Contents

PDE6B — Phosphodiesterase 6B

🧬 Gene Info
Gene SymbolPDE6B
Full NamePhosphodiesterase 6B
Chromosome4p16.3
Functionencodes a protein of 847 amino acids.
Amino Acids847 aa
Pathwayscascade: ### Dark State
UniProt IDP16404
NCBI Gene ID5159
Ensembl IDENSG00000133250
GeneCardsPDE6B
Human Protein AtlasPDE6B
N-terminal regionMediates interaction with PDE6A and regulation by PDE6G inhibitory subunits
Catalytic domainContains the phosphodiesterase active site that hydrolyzes cGMP
C-terminal regionImportant for holoenzyme assembly and membrane localization
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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