| Gene Symbol | Phosphodiesterase 5A |
| Chromosome | 4q27 |
| Protein Type | Enzyme |
| Function | encodes a cyclic nucleotide phosphodiesterase that specifically hydrolyzes cyclic guanosine monophosphate (cGMP). |
| Exons | 26 |
| UniProt ID | O76074 |
| NCBI Gene ID | 8654 |
| Ensembl ID | ENSG00000138735 |
| OMIM | 603571 |
| PDE5A1 | Full-length canonical isoform |
| PDE5A2 | Alternative N-terminus isoform |
| PDE5A3 | Testis-specific isoform |
| Synaptic plasticity | cGMP-dependent LTP and LTD |
| Memory formation | Hippocampal learning and consolidation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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