| Gene Symbol | PARD6B |
| Full Name | Partitioning Defect 6 Beta |
| Chromosome | 20q13.33 |
| Function | is a critical component of the PAR (Partitioning Defect) polarity complex that controls cell polarity establishment and maintenance in epithelial cells, neurons, and other cell types. |
| Primary Expression | brain and other tissues, with particularly high expression during development |
| Amino Acids | 372 aa |
| Exons | 10 |
| UniProt ID | [Q9UPV9](https://www.uniprot.org/uniprot/Q9UPV9) |
| Ensembl ID | ENSG00000177383 |
| OMIM | 608155 |
| GeneCards | PARD6B |
| Human Protein Atlas | PARD6B |
| C. elegans | par-6 is essential for cell polarity and asymmetric cell division |
| Drosophila | Par6 regulates epithelial polarity and neurogenesis |
| Mammals | Three isoforms (PARD6A, B, G) with tissue-specific expression |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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