| Gene Symbol | PAHX |
| Full Name | Peroxisomal 2-Hydroxyacyl-CoA Lyase |
| Chromosome | 10p13 |
| Protein Type | Enzyme |
| Function | ### Enzyme Activity and Substrate Specificity |
| Primary Expression | tissues with active peroxisomal metabolism: |
| UniProt ID | Q9NXK5 |
| NCBI Gene ID | 55627 |
| Ensembl ID | ENSG00000107882 |
| GeneCards | PAHX |
| Human Protein Atlas | PAHX |
| Substrate specificity | Prefers 2-hydroxy branched-chain fatty acyl-CoA substrates |
| Co-factor requirements | Requires CoA as a cofactor and produces acetyl-CoA as a product |
| Cellular localization | Exclusively peroxisomal matrix enzyme |
| Pathway position | Acts downstream of acyl-CoA oxidase in the beta-oxidation chain |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!