| Gene Symbol | OPRK1 |
| Full Name | Kappa Opioid Receptor |
| Aliases | KOR, OPRK |
| Chromosome | 8q11.23 |
| Protein Type | Receptor |
| Function | Dynorphins are the only known endogenous ligands with significant KOR selectivity; beta-endorphin and enkephalins bind primarily to mu and delta receptors[@bruchas2011]. |
| Primary Expression | CNS (striatum, cortex, hippocampus, hypothalamus, spinal cord), peripheral sensory neurons, immune cells |
| Molecular Weight | 48 kDa |
| Amino Acids | 426 aa |
| Pathways | MAPK pathway, PI3K |
| UniProt ID | P41145 |
| NCBI Gene ID | 4985 |
| GeneCards | OPRK1 |
| Human Protein Atlas | OPRK1 |
| Agonists | Salvinorin A (the active component of *Salvia divinorum*), U-50488, U-69593, spiradoline, enadoline |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Databases | GeneCardsHPASTRING |
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