gene 1,172 words KG: NUP214
Contents

NUP214 — Nucleoporin 214

🧬 Gene Info
Gene SymbolNUP214
Full NameNucleoporin 214 (CAN)
Chromosome9q34.13
Functionencodes a 2,090-amino acid protein with a molecular weight of approximately 214 kDa.
Primary Expressionall tissues but is particularly critical in neurons due to their dependence on efficient mRNA export for synaptic protein synthesis
Molecular Weight214 kDa
Amino Acids090 aa
UniProt IDP35658
NCBI Gene ID8021
Ensembl IDENSG00000126883
OMIM114350
GeneCardsNUP214
Human Protein AtlasNUP214
mRNA-protein complexesTranscripts encoding PSD-95, AMPA receptors, and NMDA receptors required for synaptic function
Signal transduction moleculesActivated MAPK/ERK pathway components that shuttle between nucleus and cytoplasm
Associated DiseasesAlzheimer's Disease, Acute Febrile Encephalopathy
DatabasesGeneCardsHPASTRING

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