gene 1,675 words KG: NTHL1
Contents

NTHL1 Gene

🧬 Gene Info
Gene SymbolNTHL1
Full NameNth-like DNA Glycosylase 1
Chromosome16p13.3
Protein FamilyEndonuclease III family
Functionis a DNA glycosylase that plays a critical role in the base excision repair (BER) pathway.
Molecular Weight34 kDa
Exons6
UniProt IDQ9UBC2
NCBI Gene ID4914
Ensembl IDENSG00000165030
OMIM616678
GeneCardsNTHL1
Human Protein AtlasNTHL1
Helix-hairpin-helix (HhH) motifCore catalytic domain for DNA binding
Iron-sulfur cluster (4Fe-4S)Required for structural stability and catalytic activity
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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