| Gene Symbol | NOTCH4 |
| Aliases | Page for NOTCH4 Gene |
| Chromosome | 6q23.3 |
| Protein Type | Receptor |
| Function | NOTCH4 is a member of the Notch family of transmembrane receptors that mediate cell-cell communication through conserved ligand-receptor interactions. |
| Primary Expression | endothelial cells and plays important roles in vascular development and blood-brain barrier formation |
| Pathways | NOTCH, nOTCH, Notch |
| Ensembl ID | ENSG00000204301 |
| GeneCards | NOTCH4 |
| Human Protein Atlas | NOTCH4 |
| NOTCH3 | Disease-causing gene in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) |
| ADAM10/ADAM17 | Proteases mediating NOT |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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