gene 1,794 words KG: MS4A7
Contents

MS4A7 Gene — Membrane-Spanning 4-Domains A7

🧬 Gene Info
Gene SymbolMS4A7
Full NameMembrane-Spanning 4-Domains A7
Chromosome11q12.2
Functionis a member of the MS4A (Membrane-Spanning 4-Domains subfamily A) gene family located on chromosome 11q12.
Primary Expressionmicroglia and other tissue-resident macrophages
Molecular Weight~21 kDa
Amino Acids187 aa
Exons5
UniProt IDQ9N1F0
NCBI Gene ID84236
Ensembl IDENSG00000166926
OMIM619604
GeneCardsMS4A7
Human Protein AtlasMS4A7
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (18)

TREM2-Dependent Microglial Senescence Transition
Score: 0.95
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76

Related Analyses (5)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)