gene 625 words KG: LAPTM4A
Contents

LAPTM4A Gene

🧬 Gene Info
Gene SymbolLAPTM4A
Full NameLysosomal Associated Transmembrane Protein 4 Alpha
Chromosome2p23.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues including the brain, where it supports neuronal survival and function
Subcellular LocalizationPrimarily lysosomal membranes
Amino Acids224 aa
PathwaysmTOR, mtor
UniProt ID[Q9Y3Q5](https://www.uniprot.org/uniprot/Q9Y3Q5)
Ensembl IDENSG00000137714
GeneCardsLAPTM4A
Human Protein AtlasLAPTM4A
Lysosomal membrane integrationContains multiple transmembrane domains that anchor it in the lysosomal membrane
Membrane protein interactionsInteracts with other lysosomal membrane proteins
Lysosomal pH maintenanceContributes to lysosomal acidification and function
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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