| Gene Symbol | KMT2E |
| Chromosome | 7q22.1 |
| Protein Type | Transferase |
| Function | is a human gene located on chromosome 7q22. |
| Subcellular Localization | transcription factors, involved in transcriptional activation - **SET domain:** |
| Ensembl ID | ENSG00000155438 |
| GeneCards | KMT2E |
| Human Protein Atlas | KMT2E |
| PHD finger (Plant Homeodomain) | A zinc finger domain that mediates protein-protein interactions and chromatin binding |
| FYR domain | Found in transcription factors, involved in transcriptional activation |
| SET domain | The catalytic domain responsible for histone methyltransferase activity |
| TPR repeats | Tetratricopeptide repeats mediating protein-protein interactions |
| N-terminal region | Contains sequences for nuclear localization and interaction with other chromatin regulators |
| H3K4me1 | Enhancer-associated mark, important for regulatory element activation |
| H3K4me3 | Promoter-associated mark, correlates with gene activation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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