| Gene Symbol | INPP4B |
| Full Name | Inositol Polyphosphate-4-Phosphatase Type II |
| Chromosome | 4q21.21 |
| Protein Type | Phosphatase |
| Function | is a lipid phosphatase belonging to the inositol polyphosphate phosphatase family. |
| Amino Acids | 656 aa |
| UniProt ID | [Q9NRY4](https://www.uniprot.org/uniprot/Q9NRY4) |
| Ensembl ID | ENSG00000040087 |
| OMIM | 607610 |
| GeneCards | INPP4B |
| Human Protein Atlas | INPP4B |
| Metal ion-dependent catalysis | Requires Mg²⁺ or Mn²⁺ |
| Active site residues | Cysteine nucleophile attacks the phosphate |
| Substrate specificity | Prefers PI(3,4)P₂ and PI(4,5)P₂ |
| Product release | Generates PI(3)P or PI(4)P |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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