| Gene Symbol | INNPP5D |
| Full Name | Inositol Polyphosphate-5-Phosphatase D |
| Chromosome | 2q37.1 |
| Function | INPP5D encodes SHIP1 (Src homology 2 domain-containing inositol phosphatase 1), a phosphatase that converts PIP3 to PI(3,4)P2, thereby negatively regulating PI3K/Akt signaling. |
| Primary Expression | hematopoietic cells, including microglia in the brain |
| Amino Acids | 1190 aa |
| Exons | 13 |
| UniProt ID | Q13596 |
| NCBI Gene ID | 3635 |
| Ensembl ID | ENSG00000168918 |
| OMIM | 601582 |
| GeneCards | INNPP5D |
| Human Protein Atlas | INNPP5D |
| Phosphatase domain | catalytic domain with HCX5R motif common to inositol phosphatases |
| C2 domain | involved in lipid binding and membrane localization |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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