| Gene Symbol | HRH4 |
| Full Name | Histamine Receptor H4 |
| Chromosome | 18p11.21 |
| Function | HRH4 encodes the H4 histamine receptor. |
| Primary Expression | the brain and play roles in cognitive function, attention, and motor control |
| UniProt ID | [Q9Y5N2](https://www.uniprot.org/uniprotkb/Q9Y5N2/entry) |
| GeneCards | HRH4 |
| Human Protein Atlas | HRH4 |
| HRH1, HRH2, HRH3 Genes | Other histamine receptor family members with distinct pharmacology and neural functions |
| Histamine | Primary ligand for H4 receptor signaling |
| Microglia | Primary H4-expressing brain cells involved in neuroinflammation |
| NF-κB Pathway | Key transcription factor cascade downstream of H4 signaling |
| Neuroinflammation | Central process mediating H4 receptor contribution to neurodegeneration |
| Associated Diseases | Inflammation, allergy |
| Databases | GeneCardsNCBI GeneHPASTRING |
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