| Gene Symbol | HRH2 |
| Full Name | HRH2 — Histamine Receptor H2 |
| Aliases | Histamine Receptor H2 |
| Chromosome | 5q35.2 |
| Protein Type | Gene |
| Function | encodes a 391-amino acid protein that signals primarily through Gs proteins, leading to increased intracellular cAMP levels. |
| Amino Acids | 391 aa |
| Exons | 4 |
| NCBI Gene ID | 3374 |
| GeneCards | HRH2 |
| Human Protein Atlas | HRH2 |
| Transmembrane domains | Seven α-helices that traverse the plasma membrane |
| Ligand-binding pocket | Formed by TM3, TM5, TM6, and TM7 |
| G-protein coupling domain | Located on intracellular loops 2 and 3 |
| Phosphorylation sites | Serine and threonine residues on the C-terminus for receptor regulation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtHPASTRING |
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