| Gene Symbol | HMOX2 |
| Protein Type | Enzyme |
| Function | HMOX2 (Heme Oxygenase 2) is a constitutively expressed heme oxygenase enzyme that catalyzes the degradation of heme into biliverdin, iron, and carbon monoxide (CO) |
| Amino Acids | 316 aa |
| GeneCards | HMOX2 |
| Human Protein Atlas | HMOX2 |
| N-terminal membrane anchor | A hydrophobic sequence that localizes HMOX2 to the ER membrane |
| Heme oxygenase domain | The catalytic domain that binds and degrades heme |
| C-terminal region | Involved in substrate access and protein interactions |
| Biliverdin | Converted to bilirubin, both acting as antioxidants |
| Iron | Induces ferritin synthesis for safe storage |
| Carbon monoxide | Important signaling molecule |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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